CB-618 sodium salt
CAS No. 1628207-16-8
CB-618 sodium salt( CB 618 | CB 238618 )
Catalog No. M12422 CAS No. 1628207-16-8
CB-618 (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameCB-618 sodium salt
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NoteResearch use only, not for human use.
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Brief DescriptionCB-618 (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates.
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DescriptionCB-618 (CB 238618) is a novel non-β-lactam β-lactamase inhibitor that potentiates meropenem MIC values against clinical Enterobacteriaceae isolates; displays a minimal antibacterial effect alone, potentiates the meropenem MIC values of 16-512 mg/ml to 0.25-2 mg/ml.
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In Vitro——
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In Vivo——
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SynonymsCB 618 | CB 238618
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number1628207-16-8
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Formula Weight312.23
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Molecular FormulaC8H10N4O6S.Na
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Purity>98% (HPLC)
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Solubility——
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SMILESC1CC(N2CC1N(C2=O)OS(=O)(=O)[O-])C3=NN=CO3.[Na+]
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Chemical Name(1R,2S,5R)-2-(1,3,4-oxadiazol-2-yl)-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate, sodium salt
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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J8-C8
J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.
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GSK-1322322
A novel antibacterial agent that targets bacterial peptide deformylase; demonstrates in vitro activity against MDR respiratory and skin infection pathogens.
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N-Acetyltyramine
N-Acetyltyramine is the active compound extracted from a fermentation broth of strain M3-10 which produces quorum-sensing inhibitor (QSI) compound. N-Acetyltyramine inhibits Chromobacterium violaceum ATCC 12472 violacein production and virulence factors, such as pyoverdine production, as well as swarming and twitching motilities, produced by Pseudomonas aeruginosa PAO1.
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